Deca Durabolin: Uses, Benefits, And Side Effects
What is 2 O‑Methyl‑5‑Hydroxy‑1‑Phenyl (A.k.a. "2‑O‑Methyl Dianabol" or "2‑O‑Methyldianabol")?
| Feature | Description |
|---|---|
| Chemical name | 2‑O‑methyl‑5‑hydroxy‑1‑phenyl‑3‑undecanone (a methyl ether of the hydroxyl group on the classic Dianabol). |
| Structure | It’s a derivative of the anabolic steroid Methandrostenolone (Dianabol) where the 2‑OH is replaced by an O‑CH₃ group. |
| Stereochemistry | The same chiral centers as Dianabol; no new stereocenters are introduced. |
| Pharmacology | An androgenic steroid with anabolic properties; more lipophilic due to the ether, potentially improving oral bioavailability and reducing first‑pass metabolism. |
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How It Differs from Standard Steroids
- Metabolic Stability
- This may prolong systemic circulation and increase oral potency.
- Lipophilicity & Absorption
- Oral bioavailability can be higher than for steroids with free hydroxyl groups at the same site.
- Pharmacokinetics
- Therapeutic Profile
- Potentially useful in conditions like rheumatoid arthritis, inflammatory bowel disease, or organ transplant rejection where long‑acting steroids are preferred.
- Safety Considerations
- Careful dose titration and monitoring would be essential.
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Bottom line:
A steroid bearing an O‑substituted aromatic ring is more lipophilic, better absorbed, metabolized more slowly, and therefore has a longer duration of action. Such a compound could provide strong, sustained anti‑inflammatory effects but would also require vigilant management of dose‑related adverse events.
